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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

La La Land producer Jordan Horowitz returned to the microphone after being told about the mix up and said 'Moonlight won Best Picture' and insisting that 'this is not a joke'.
迁移工程也是京津冀一体化计划的一部分,其目的在于缓解首都交通拥挤,为地区提供更加均衡的发展。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

AR could be the bigger opportunity after Apple’s Tim Cook gave the technology his backing — it was included in Apple’s latest operating system and its iPhone X device.
肠道细菌正以我们想像不到的方式干扰着我们。新的研究指出,像帕金森综合症等神经退行性疾病实际上可能始于肠道,而不是大脑。越来越多的证据显示,慢性疲劳综合征可能要归咎于人体内的微生物群系。随着肠道细菌显示出控制食欲以及改变大脑结构的迹象,而且有引起大脑损伤而导致中风的表现,我们的这个小过客(肠道细菌)有着不容忽视的力量。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

2013 Rank: 14

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

"Migration should be an option, a choice. But for 200 million people, it's a necessity," he told the Thomson Reuters Foundation in a phone interview.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

2013年排名:3
Dunkirk
从2016年6月1日至2017年6月1日,世界上收入最高的十位模特的税前总收入不算各项费用共计为1.095亿美元。
这一点毋庸置疑。从卫生间标志到时装秀,性别界线正在加速变得模糊。现在我们差不多该抛弃传统的“女孩用粉色,男孩用蓝色”的成见了。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

全球最佳大学排行榜是根据科睿唯安公司提供的数据和标准得出的。
内森说:“如今,你必须根据行情购买。不过,如果你很大胆,不跟随潮流,那么你也有很多机会。”
“As we work to keep and attract more young professionals and job creators, we appreciate every young person who is engaged and invested in our state.”
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

May you have the best New Year ever.愿你度过最美好的新年!

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 卫浴市场“明折暗扣”背后的真相
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

It was the age of wisdom, it was the age of foolishness…

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

slouch
The rise of ephemeral social networks

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

It was the fastest growth rate among the top 10 countries on the EPO's patent-filing league table.
The list has four British universities, which are Cambridge, Oxford and London's University College and Imperial College. The University of Tokyo is also included in top 20.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

有的时候,老板挺糟糕的。但如果你觉得你的老板一直很差劲,占用了你的时间,是的,你该去找一份新的工作了。
夏洛特·艾玛·艾奇逊《1号天使》

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

No, this doesn't mean you should abandon your LinkedIn profile for fear of a suspicious boss. But it does mean you should be more careful. For one, turn off your activity broadcasts so that every savvy move you make isn't announced to your entire network. Here's how: From the homepage, hover over your photo in the top right corner, and click on "Privacy & Settings." From this page, click "Turn on/off your activity broadcasts."
发布日期:2015年
5. 格罗斯警告:“庞氏骗局!临界点!信贷超新星!”
5. Smart belt

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

While the WeChat use of the "post-90s" generation has slightly decreased, from 94.1 percent to 86.6 percent.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The artefact which has a flat base was found inside an ancient tomb in the Xuyi County in western Jiangsu in 2009. It has been kept at the Nanjing Museum the capital of Jiangsu Province.
No. What has been billed as the largest ever IPO is a cornerstone of de facto leader Mohammed bin Salman’s grand economic restructuring, so it must happen. Shares in Aramco will be quoted on the local stock exchange. The international element of the IPO is unlikely to be a public listing, however. Donald Trump has lobbied for New York, and London is pulling all the stops. Hong Kong and Tokyo are also under consideration. But the Saudis will opt instead for a private sale, or choose to list internationally later than anticipated.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

据国际足联秘书长杰罗姆·瓦尔克说,贝老爷子的1950年版门票将在苏黎世的一家博物馆展出,展览定于2015年开放。他还说:“这版球票很稀有,我们希望博物馆能够珍藏。”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 降低社保费率需要“全国一盘棋”
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

1.Photography: 22.3 percent increase

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

而在进口一侧,不论以人民币还是美元计,情况都愈发糟糕。
每平方英尺单价:310美元(每平方米约合人民币2.1万元)
最佳豪华汽车品牌:保时捷
抓好金融体制改革。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Gunal Youssouf, 23, is a Teach Firster who has joined the UK arm of PwC’s management consultancy graduate scheme. She says the two-year program-me gave her a chance to taste teaching without the cost of studying for a traditional qualification.
The life expectancy of the average human has increased more in the past 50 years than it did in the 200,000 years of human existence. Life expectancy is now 70 years old – which is a big difference from 47 years old in 1950!
不过,增长疲软对年终奖的影响或许在2015年已见顶。当时,66%的白领员工没有收到年终奖。而2016年的比例实际上比2014年都有所好转,那一年未收到年终奖的比例为61%。
[tr?ns'p?:t]
Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 新房质量验收 呼唤独立验房机制
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Citing recent figures from the CPB Netherlands Bureau for Policy Analysis, that show global trade in seasonally-adjusted volume terms fell 1.1 per cent between September and October, Mr Leering suggests last year will prove to be the worst year for world trade since 2009.
4.英国人似乎总是喜欢道歉,但道歉的意义并不相同。在英国,“对不起”实际可能表示这几种意思:(1)我没听清你说什么;(2)我没明白你的意思;(3)我听到了你说的,也明白你的意思,可我觉得你是个白痴。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

如果你有幸拥有一份工作,那么想要辞掉这份工作的想法听起来是荒唐的。在失业率大多数有史以来的最高的今天,大多数人正在因为被聘用而感谢他们的幸运星。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

2018年,将会有更多商业领袖利用数字化、代际变动和多元化不断提高的强大结合,来精简企业层级结构,分配责任,转变他们所在的组织。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

“多年以来,我们看到中国增长势如破竹,而美国增长率却在下降,”保险商耆卫(Old Mutual)旗下资产管理公司Old Mutual Global Investors的亚洲股票业务主管乔希?克拉布(Josh Crabb)说,“但是,交易量下降得相当厉害,所以我们并不真的确定当前价格到底如何。看起来,香港市场的基本面展望非常严峻。”
导演贝尼特·米勒(Bennett Miller)认为卡瑞尔是饰演杜邦的合适人选,但不想让观众一眼就认出他来。他要求造型师比尔·科森(Bill Corso)改变卡瑞尔的外貌。
《三生三世十里桃花》是唐七在2009年出版的一部网络小说。今年,这部作品被改编成电影、电视剧以及电脑游戏。
安迪?穆雷在美国男子网球公开赛中取得的胜利和奥运夺冠使他成为搜索次数最多的英国奥运会选手。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

['dev?steiti?]
Both the film and the television series are adapted from the Taiwan action role-playing game of the same name which was developed by Softstar Entertainment. The game is considered by many as simply one of the best Chinese RPG's ever created.
Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.
《法律与秩序:特殊受害者》(Law & Order: SVU):NBC频道的这部电视剧上一季中的危机仿佛是从肥皂剧中搬来,发生了各种大事,奥利维亚(Olivia,玛莉丝卡·哈吉塔[(Mariska Hargitay]饰)经历了许多危险——喜欢跟踪的变态强奸犯,折磨人的婚外恋,新生婴儿,现在这一切终于平息下来。在今年的第16季中,侦探们回到了重要的性犯罪上,其中一集的灵感来自雷·赖斯(Ray Rice),讲述的是从监控录像中看到一个著名体育广播员殴打自己的妻子。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

因为中国严格的政策,该内衣品牌的几位最有名的模特无法出席今年最重要的活动,上周吉吉·哈迪德就在推特上表示她不会出席此次维密秀。
[p?izd]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 毕业证与就业协议应彻底“脱钩”
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

[s?:'vei]
单词receptive 联想记忆:
According to the index, tourists are "spending overwhelmingly" to shop -- and not to dine -- in the top 20 destinations outside of Europe, despite many of them being world-famous cuisine capitals.
Dealers: Car dealers work toward reducing the paperwork involved in buying a car and the hours it takes to fill it out. That will give them more time to devote to upselling add-ons such as extended warranties, paint and fabric protection, and rust-proofing.
不过,日本央行(BoJ)仍决定不加大货币政策刺激力度。该行指出,工业产出是日本经济疲软的领域之一。当然,就业市场等日本经济的其他领域,表现要好得多。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

丝绸之路上的城市
[k?ut?]
Maddie has now appeared in three of Sia's videos - Chandelier, Elastic Heart and Big Girls Cry.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 2014年中国瓷砖总产量或首破百亿
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

其关于朋友间爱情、事业、友谊的主题仍然与今天的年轻人息息相关。
7. 建立声誉。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

When Dickens wrote about the French Revolution in A Tale of Two Cities, he did it with nearly a century of hindsight. Here, at the end of December, I don’t enjoy that luxury. As such, some of the trends I’ve written here are likely to remain in force for the foreseeable future, while others may have already begun to fade. As one of this period’s “noisiest authorities,” I insist only on your receiving this review with just one caveat in mind: Past performance does not guarantee future results.
总排名76位的新加坡管理大学(Singapore Management University)李光前商学院(Lee Kong Chian School of Business)是首家进入这一排行榜的新加坡商学院。今年共7家亚洲商学院上榜。李光前商学院校友在亚洲商学院中最具国际流动性。他们在流动性指标方面排名第25,比在亚洲商学院中流动性排第二的台湾国立中山大学(National Sun Yat-Sen University)高57位。
Zheng Gang, a member of the CPPCC National Committee and deputy mayor of Danzhou city, Hainan province.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 毕业租房 这些窍门要知道
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Foss 还指出别人的推荐信有时间标记。如果你一周之内有五个新的赞那样看起来会很可疑,这些赞不像是真心的,好像你在刷好评,让别人说你好。
请接受我们对你及你全家的美好祝福,祝你们新年快乐。
担忧和愤怒要深刻得多,也更不吸引人。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

adj. 终极的,根本

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

会。在2018年美联储可能多次加息的情况下,新兴市场中的交易可能会波动起伏。有时可能感觉有点像2013年“削减恐慌”(taper tantrum)重演。然而,平均GDP增速将升至5%,高于去年4.7%的预测值。这主要是因为近来处境艰难的俄罗斯和巴西境况将好转。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

We learned that there is new hope for Africans with treatable cancers.
[nju:'tris]

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

教育部在一场新闻发布会上表示,全球大多数的留学生都是来自中国。
“我还给了他一个直言不讳的同性恋朋友,他会责备邦德,说:‘拜托,邦德,你是生活在20世纪,不是中世纪。’”
3. Portugal is entirely powered by renewable energy for four days
n. 罪犯

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 房地产调控成果来之不易
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

vt. 控制
If a sitcom that lasts for 10 years is considered popular, then surely one that still stirs up emotions after 20 must be considered a classic. Friends first aired in the US in 1994, featuring a cast of six young men and women in New York. In the time since, it’s become one of the most famous titles in the sitcom genre, aired in over 100 countries and regions in the world.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

"A total of 297 projects will be carried out in Tongzhou, such as building new subway lines and expressways, and improving ecologies," Lu Yan, director of the Beijing Municipal Commission of Development and Reform, said at a news conference on Wednesday.
6. How to play guitar

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

vt. 打斗

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

vt. 作 ... 姿
Price growth in top cities was slower, however, with Beijing, for instance, reporting a rise of only 0.5 per cent from the previous month, compared to 4.9 per cent in September.
3.数学家
The pear-shaped diamond named The Blue is 13.22 carats is estimated to be worth between $21-$25 million.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 超80万高校毕业生在广东求职
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

em进入,brace胳膊-拥抱
6. You don’t just pass in front of the TV if i’m watching football, you better crawl on the floor.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 房企融资放松?市场误读了发改委
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

adj. 浪漫的
这句话是唯一来自现实世界而不是网络的。一位政府官员在回答《焦点访谈》记者“天津市每年要偿还公路建设的贷款量有多大”的问题时,回答到“这事儿不能说太细”,网民们觉得这句话很有意思,于是流传甚广。
“Even though there is significant awareness [of the role of Fed policy], market dynamics can become unstable or unfavourable relatively easily,” he says. “Then you get into a self-reinforcing cycle of selling pressure.”

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

一部富有感染力的、描写一名年轻黑人男同性恋成长故事的影片《月光男孩》(Moonlight),获得2017年奥斯卡(Oscar)最佳影片奖。不过,该片险些与此奖项擦肩而过,原因是在混乱的颁奖现场,此奖项曾被误颁给了《爱乐之城》(La La Land)。
“一国两制”的实践要不动摇、不走样、不变形。
去年,中国工商银行的每股盈利为0.77元人民币,低于上一年的0.78元人民币,税前每股分红为0.2333元人民币,低于上一年的0.2554元人民币。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

“而在市场上前所未有的是确实有客户在寻找这样的投资。”
“Why do we keep getting so many record-warm years?” Dr. Schmidt asked in an interview. “It’s because the planet is warming. The basic issue is the long-term trend, and it is not going away.”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 资产证券化成了长租公寓的毒药?
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

On 2 March, the North's state-run website Uriminzokkiri warned that Pyongyang would respond to any balloon launches with "not just a few shots of gunfire but cannons or missiles".
Chris Washington, played by London-born Daniel Kaluuya, is drawn into the sinister underbelly of a small American community.
库什纳回忆道,我当时被他深深折服了。他到新闻集团去见默多克时,我与他有了第一次接触,当时我被一同叫去提提意见。达洛伊西奥在会上描述了他想要实现的远景。他帮助默多克加深了对一些事物的见解。达洛伊西奥在台上的优异表现,加上背后李嘉诚的雄厚财力,为Summly招来了包括艾什顿?库奇(Ashton Kutcher)、小野洋子(Yoko Ono)、史蒂芬?弗莱(Stephen Fry)等许多人的捐赠。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

n. 补给,供给,供应,贮备
考察指标包括“智力资本和创新”、“技术成熟度”、“区域重要城市”、“健康、安全与治安”、“交通和城市规划”、“可持续发展与自然环境”、“文化与居民生活”、“经济影响力”、“成本”和“宜商环境”。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

201001/93725.shtml
Transforming and upgrading the real economy through innovation
沿海江苏省的无锡市以4.9%的环比涨幅连续第二个月处于首位。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

孙俪在剧中扮演女主周莹。虽然孙俪是1982年生人,但在许多观众眼中,她仍然成功塑造了一个可爱天真的少女周莹。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Take targeted and powerful measures to strengthen areas of weakness.
8 April

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

今年到目前为止,周星驰的《美人鱼》自二月上旬的贺岁档上映以来,已经取得了5.26亿美元的票房收入。
今年到目前为止,周星驰的《美人鱼》自二月上旬的贺岁档上映以来,已经取得了5.26亿美元的票房收入。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

上海实施新措施一年以来,受理外籍人士及其家属永久居留申请同比增长6倍。
Transforming and upgrading the real economy through innovation

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

为提高中国足球在国际赛场上的竞争力,中国政府日前公布了最新的足球发展计划,将在2017年开设20000所足球专业学校,用于训练年轻球员、培养人才。
Facebook首席执行官马克扎克伯格

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

n. 小麦,小麦色

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

response
在其他地方,澳大利亚最近推出了提高基金定价透明度的改革措施,这推动了ETF的快速增长。
The board is frequently covered in equations. Have you ever wondered what those equations mean? Well, we may never know what they mean, but they are all real, accurate equations. Very impressive, Big Bang. Very impressive indeed.
Immigrant populations in Arkansas, North Carolina and Tennessee have more than tripled since 1990, noted Lee Drutman, a senior fellow at the New America Foundation, in an analysis for Vox. Anxiety over those changes may explain why the Republican Party became so much more focused on limiting immigration over that period — and why white voters in those states overwhelmingly support Mr. Trump.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

来源:前十网

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

The controlled test takes two-and-a-half hours and, according to theories, Nishi's score and subsequentIQ of 162 would be two points higher than famous physicist Einstein.
We will perform with a strong work ethic, sense of responsibility, and enterprising spirit.
A schoolgirl aged 11 has been honoured as "America's top young scientist" for inventing a quick, low-cost test to detect lead-contaminated water.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

4、优衣库事件
巴里摩尔的病情基于米歇尔·菲利普斯的真实生活,她的头部在在两次机动车事故中受伤,记忆只能维持24小时。桑德勒用录像带,菲利普斯则是用便利贴和手机(对她而言还真时髦)撑了23年。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 中介须尽职 谨防买卖双方有纠纷
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

n. 声明,陈述
Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

2月CPI同比上涨2.3%,高于预期的1.8%,为2014年7月以来最大涨幅。1月CPI同比上涨1.8%。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

数据显示,三星仍然占据榜首,其次是苹果。但是即便如此,这前两名的科技公司的出货量却分别下降了3%和7%,全球市场份额出现了下滑。
4. Stop eating, gotta get those cheekbone sharp enough to cut butter.
许多人在学习小组中受益良多。你得有条有理地进行,不能拖延时间。你要将学习的内容彻底消化,并能够向别人复述出来。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

麦高恩早年的成功依靠于发行独立电影,当时她在酒店房间遇到哈维·韦恩斯坦,就是在那间房里遭受了性侵。
0=不是
最佳乐队组合:Little Big Town
3. Elasticity of Demand.The cure for low prices is low prices. That cliché can be applied to both the supply and demand side of the equation. Will oil selling at fire sale prices spur renewed demand? In some countries where oil is more regulated, low prices may not trickle down to the retail level. Countries like Indonesia are scrapping subsidies, which will be a boon to state coffers but will diminish the benefits to consumers. However, in the U.S., gasoline prices are now below $2.40 per gallon, more than 35 percent down from mid-2014. That has led to an uptick in gasoline consumption. In the waning days of 2014, the U.S. consumed gasoline at the highest daily rate since 2007. Low prices could spark higher demand, which in turn could send oil prices back up.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

在经过一段漫长而艰辛的竞选活动后,美国当地时间11月6日,美国总统奥巴马战胜了共和党候选人罗姆尼,胜出2012美国总统大选成功连任,将迎来执政白宫的第二个任期。
户外空间:这栋房屋占地面积五分之一英亩(约809平方米)由纽约公司Landgarden负责景观设计。房屋前面的这座日式花园中采用了当地的植物。这栋房屋后面还有一处露台和院子,那里还有一座日式花园。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 房地产调控总基调没有变
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

单词circulation 联想记忆:
但他认为自己任教的经历非常宝贵,可以让他很快适应新的职业阶段。
荷兰首相马克?吕特(Mark Rutte)最近由于对安卡拉立场强硬而在民调中排名上升。吕特所属的自由民主人民党(VVD)在民调中略微领先自由党。周二,他将埃尔多安的言论称为“对历史令人恶心的歪曲”,还称“我们不会自甘堕落至这种水平。这完全不可接受”。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 190套大套型公租房今起登记
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About this collection

Premiered in August, the 48-episode TV series is a fictional story, with a plot centering on struggles and romance during the Qin Dynasty (221-206 BC).
位居榜单第三的是史蒂夫·卡瑞尔(Steve Carell)。《卑鄙的我2》(Despicable Me 2)在今年大获成功,斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房,该系列第三部《小黄人》(Minions)也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》(The Way Way Back)和《超级魔术师》(The Incredible Burt Wonderstone)。后一部影片的票房虽未能赚回制作成本,但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。

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