Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
La La Land producer Jordan Horowitz returned to the microphone after being told about the mix up and said 'Moonlight won Best Picture' and insisting that 'this is not a joke'.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
AR could be the bigger opportunity after Apple’s Tim Cook gave the technology his backing — it was included in Apple’s latest operating system and its iPhone X device.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
2013 Rank: 14
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
"Migration should be an option, a choice. But for 200 million people, it's a necessity," he told the Thomson Reuters Foundation in a phone interview.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Trends and targets in antiviral phototherapy
“As we work to keep and attract more young professionals and job creators, we appreciate every young person who is engaged and invested in our state.”
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
May you have the best New Year ever.愿你度过最美好的新年！
Novel biosensing methodologies for ultrasensitive detection of viruses
It was the age of wisdom, it was the age of foolishness…
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The rise of ephemeral social networks
ACE2 as a potential therapeutic target for pandemic COVID-19
It was the fastest growth rate among the top 10 countries on the EPO's patent-filing league table.
The list has four British universities, which are Cambridge, Oxford and London's University College and Imperial College. The University of Tokyo is also included in top 20.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
No, this doesn't mean you should abandon your LinkedIn profile for fear of a suspicious boss. But it does mean you should be more careful. For one, turn off your activity broadcasts so that every savvy move you make isn't announced to your entire network. Here's how: From the homepage, hover over your photo in the top right corner, and click on "Privacy & Settings." From this page, click "Turn on/off your activity broadcasts."
5. Smart belt
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
While the WeChat use of the "post-90s" generation has slightly decreased, from 94.1 percent to 86.6 percent.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
The artefact which has a flat base was found inside an ancient tomb in the Xuyi County in western Jiangsu in 2009. It has been kept at the Nanjing Museum the capital of Jiangsu Province.
No. What has been billed as the largest ever IPO is a cornerstone of de facto leader Mohammed bin Salman’s grand economic restructuring, so it must happen. Shares in Aramco will be quoted on the local stock exchange. The international element of the IPO is unlikely to be a public listing, however. Donald Trump has lobbied for New York, and London is pulling all the stops. Hong Kong and Tokyo are also under consideration. But the Saudis will opt instead for a private sale, or choose to list internationally later than anticipated.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
1.Photography: 22.3 percent increase
Antiviral drug discovery: broad-spectrum drugs from nature
Influenza neuraminidase: A druggable target for natural products
Gunal Youssouf, 23, is a Teach Firster who has joined the UK arm of PwC’s management consultancy graduate scheme. She says the two-year program-me gave her a chance to taste teaching without the cost of studying for a traditional qualification.
The life expectancy of the average human has increased more in the past 50 years than it did in the 200,000 years of human existence. Life expectancy is now 70 years old – which is a big difference from 47 years old in 1950!
Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Citing recent figures from the CPB Netherlands Bureau for Policy Analysis, that show global trade in seasonally-adjusted volume terms fell 1.1 per cent between September and October, Mr Leering suggests last year will prove to be the worst year for world trade since 2009.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
“多年以来，我们看到中国增长势如破竹，而美国增长率却在下降，”保险商耆卫(Old Mutual)旗下资产管理公司Old Mutual Global Investors的亚洲股票业务主管乔希?克拉布(Josh Crabb)说，“但是，交易量下降得相当厉害，所以我们并不真的确定当前价格到底如何。看起来，香港市场的基本面展望非常严峻。”
导演贝尼特·米勒(Bennett Miller)认为卡瑞尔是饰演杜邦的合适人选，但不想让观众一眼就认出他来。他要求造型师比尔·科森(Bill Corso)改变卡瑞尔的外貌。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Both the film and the television series are adapted from the Taiwan action role-playing game of the same name which was developed by Softstar Entertainment. The game is considered by many as simply one of the best Chinese RPG's ever created.
Faber laughs at Bernanke's remark that the economy would be strong enough later this year so he could take his foot off the gas, that is begin 'tapering, or scaling back it's stimulative quantitative easing (QE) program later this year.' Yes, laughed.
《法律与秩序：特殊受害者》(Law & Order: SVU)：NBC频道的这部电视剧上一季中的危机仿佛是从肥皂剧中搬来，发生了各种大事，奥利维亚（Olivia，玛莉丝卡·哈吉塔[(Mariska Hargitay]饰）经历了许多危险——喜欢跟踪的变态强奸犯，折磨人的婚外恋，新生婴儿，现在这一切终于平息下来。在今年的第16季中，侦探们回到了重要的性犯罪上，其中一集的灵感来自雷·赖斯(Ray Rice)，讲述的是从监控录像中看到一个著名体育广播员殴打自己的妻子。
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
According to the index, tourists are "spending overwhelmingly" to shop -- and not to dine -- in the top 20 destinations outside of Europe, despite many of them being world-famous cuisine capitals.
Dealers: Car dealers work toward reducing the paperwork involved in buying a car and the hours it takes to fill it out. That will give them more time to devote to upselling add-ons such as extended warranties, paint and fabric protection, and rust-proofing.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Maddie has now appeared in three of Sia's videos - Chandelier, Elastic Heart and Big Girls Cry.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
When Dickens wrote about the French Revolution in A Tale of Two Cities, he did it with nearly a century of hindsight. Here, at the end of December, I don’t enjoy that luxury. As such, some of the trends I’ve written here are likely to remain in force for the foreseeable future, while others may have already begun to fade. As one of this period’s “noisiest authorities,” I insist only on your receiving this review with just one caveat in mind: Past performance does not guarantee future results.
总排名76位的新加坡管理大学(Singapore Management University)李光前商学院(Lee Kong Chian School of Business)是首家进入这一排行榜的新加坡商学院。今年共7家亚洲商学院上榜。李光前商学院校友在亚洲商学院中最具国际流动性。他们在流动性指标方面排名第25，比在亚洲商学院中流动性排第二的台湾国立中山大学(National Sun Yat-Sen University)高57位。
Zheng Gang, a member of the CPPCC National Committee and deputy mayor of Danzhou city, Hainan province.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
We learned that there is new hope for Africans with treatable cancers.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
3. Portugal is entirely powered by renewable energy for four days
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
If a sitcom that lasts for 10 years is considered popular, then surely one that still stirs up emotions after 20 must be considered a classic. Friends first aired in the US in 1994, featuring a cast of six young men and women in New York. In the time since, it’s become one of the most famous titles in the sitcom genre, aired in over 100 countries and regions in the world.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
"A total of 297 projects will be carried out in Tongzhou, such as building new subway lines and expressways, and improving ecologies," Lu Yan, director of the Beijing Municipal Commission of Development and Reform, said at a news conference on Wednesday.
6. How to play guitar
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
vt. 作 ... 姿
Price growth in top cities was slower, however, with Beijing, for instance, reporting a rise of only 0.5 per cent from the previous month, compared to 4.9 per cent in September.
The pear-shaped diamond named The Blue is 13.22 carats is estimated to be worth between $21-$25 million.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
6. You don’t just pass in front of the TV if i’m watching football, you better crawl on the floor.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
“Even though there is significant awareness [of the role of Fed policy], market dynamics can become unstable or unfavourable relatively easily,” he says. “Then you get into a self-reinforcing cycle of selling pressure.”
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
一部富有感染力的、描写一名年轻黑人男同性恋成长故事的影片《月光男孩》(Moonlight)，获得2017年奥斯卡(Oscar)最佳影片奖。不过，该片险些与此奖项擦肩而过，原因是在混乱的颁奖现场，此奖项曾被误颁给了《爱乐之城》(La La Land)。
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
“Why do we keep getting so many record-warm years?” Dr. Schmidt asked in an interview. “It’s because the planet is warming. The basic issue is the long-term trend, and it is not going away.”
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
On 2 March, the North's state-run website Uriminzokkiri warned that Pyongyang would respond to any balloon launches with "not just a few shots of gunfire but cannons or missiles".
Chris Washington, played by London-born Daniel Kaluuya, is drawn into the sinister underbelly of a small American community.
库什纳回忆道，我当时被他深深折服了。他到新闻集团去见默多克时，我与他有了第一次接触，当时我被一同叫去提提意见。达洛伊西奥在会上描述了他想要实现的远景。他帮助默多克加深了对一些事物的见解。达洛伊西奥在台上的优异表现，加上背后李嘉诚的雄厚财力，为Summly招来了包括艾什顿?库奇(Ashton Kutcher)、小野洋子(Yoko Ono)、史蒂芬?弗莱(Stephen Fry)等许多人的捐赠。
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Transforming and upgrading the real economy through innovation
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Take targeted and powerful measures to strengthen areas of weakness.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Transforming and upgrading the real economy through innovation
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The board is frequently covered in equations. Have you ever wondered what those equations mean? Well, we may never know what they mean, but they are all real, accurate equations. Very impressive, Big Bang. Very impressive indeed.
Immigrant populations in Arkansas, North Carolina and Tennessee have more than tripled since 1990, noted Lee Drutman, a senior fellow at the New America Foundation, in an analysis for Vox. Anxiety over those changes may explain why the Republican Party became so much more focused on limiting immigration over that period — and why white voters in those states overwhelmingly support Mr. Trump.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
The controlled test takes two-and-a-half hours and, according to theories, Nishi's score and subsequentIQ of 162 would be two points higher than famous physicist Einstein.
We will perform with a strong work ethic, sense of responsibility, and enterprising spirit.
A schoolgirl aged 11 has been honoured as "America's top young scientist" for inventing a quick, low-cost test to detect lead-contaminated water.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
4. Stop eating, gotta get those cheekbone sharp enough to cut butter.
Length-scale dependence of protein hydration-shell density
最佳乐队组合：Little Big Town
3. Elasticity of Demand.The cure for low prices is low prices. That cliché can be applied to both the supply and demand side of the equation. Will oil selling at fire sale prices spur renewed demand? In some countries where oil is more regulated, low prices may not trickle down to the retail level. Countries like Indonesia are scrapping subsidies, which will be a boon to state coffers but will diminish the benefits to consumers. However, in the U.S., gasoline prices are now below $2.40 per gallon, more than 35 percent down from mid-2014. That has led to an uptick in gasoline consumption. In the waning days of 2014, the U.S. consumed gasoline at the highest daily rate since 2007. Low prices could spark higher demand, which in turn could send oil prices back up.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
About this collection
Premiered in August, the 48-episode TV series is a fictional story, with a plot centering on struggles and romance during the Qin Dynasty (221-206 BC).
位居榜单第三的是史蒂夫·卡瑞尔（Steve Carell）。《卑鄙的我2》（Despicable Me 2）在今年大获成功，斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房，该系列第三部《小黄人》（Minions）也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》（The Way Way Back）和《超级魔术师》（The Incredible Burt Wonderstone）。后一部影片的票房虽未能赚回制作成本，但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。